Voltage-Gated Potassium Channel Kv1.3 as a Target in Therapy of Cancer
Voltage-gated potassium channel Kv1.3 is an integral membrane protein, which is selectively permeable for potassium ions and is activated upon a change of membrane potential.Channel activation enables transportation of potassium ions down their electrochemical gradient.Kv1.3 channel is expressed in many cell types, both normal and cancer.Activity o